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Senior Scientist GMU CMC Cell Culture Process Development

Waltham, Massachusetts



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PositionOverview/Department Description 

The Genomic Medicine Unit (GMU) CMC group at Sanofi is dedicated to the establishment of best in class manufacturing platforms to support development of life-changing advanced cell and gene therapy products, including recombinant AAV vectors, lentiviral vectors and cell therapy products.  Sanofi is looking for an experienced cell culture development professional with experience in viral vector production to join the Genomic Medicine Cell Culture Process Development Group located in Waltham, MA in the role ofSenior Scientist.  The Genomic Medicine Cell Culture Development group within Sanofi operates with the mission to develop robust, scalable and innovative viral vector cell culture processes for Sanofi’s genomic medicine pipeline. The successful applicant will lead a group of scientists and engineers responsible for the development of viral vector cell culture processes, technology transfer to manufacturing sites,overseeing process scale up operations, defining scale down models, and authoring of associated regulatory filing activities.We are looking for a candidate with excellent scientific, communication, and project management skills.  

Job Duties and Responsibilities

  • Lead a small group of scientists and engineers focused on upstream process developmentproviding strong technical leadership

  • Contribute to project, technical, and strategic teams as appropriate

  • Effectively manage a multi project development portfolio

  • Make strong technical strategic contributions to cross functional development project teams to ensure efficient and timely execution of deliverables

  • Mentordirect reportsin specific lab techniques and /or processes

  • Establish and driveinnovation in furthering scientific and process understanding to enhance viral vector productivityand quality.

  • Independentlyplan and lead the execution of upstream process development for assets in all stages of the development life cycle

  • Plan resourcesfor supported projectsto ensure timelydelivery of department objectives

  • Serve as a subject matter expert in one or more selected areas of cell culture development and support the entire upstream development portfolio

  • Present findings and/or results to senior management, external stakeholders, and industry leaders at national/international conferences.

  • Contribute to manuscript and patent writing for external publications and patent applications.

Basic Qualifications

  • PhD degree in Biotechnology, Cell Biology, Biochemistry, Chemical Engineering or relateddisciplinewitha minimum of4years of relevant experience oraMaster’s degreewitha minimum of8years of experienceor a Bachelor’sdegree with a minimum of 10 years of experience.

  • Experience in executing projects to aggressive timelines with the ability to adapt to rapid changes in project priorities.

  • Excellent communication skills 

Preferred Qualifications

  • Experience in managing one or more junior staff (either within a line function or a cross-functional project team).

  • Experience in the biotech/pharmaceutical industry within a cell culture role and an excellent understanding of the theory and practice of cell culture process development 

  • Experiencemanaging cross functional team and initiatives.

  • Experience in media development optimization

  • Experience in the development of HeLa producer cell line production processes and/or HEK AAV transient transfection production

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.



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