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Senior Associate Scientist, Protein Biochemistry

Waltham, Massachusetts



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The Rare Blood Disorders group at Sanofi is seeking a highly motivated and talented Senior Associate Scientist to join our multidisciplinary team focused on the discovery of novel and next generation therapeutics across various rare blood diseases. The ideal candidate will possess a strong core competency in protein biochemistry, with specific expertise in studying protein:protein and/or protein:ligand interactions. She/he will support projects from discovery research into early development as an active member of a cross-functional team. The candidate will participate in regular team meetings, present results, design experiments, interpret data, and formulate conclusions. The candidate must be driven, resourceful, and able to work independently.

Responsibilities include:

  • Determining protein:protein interaction kinetics using real time binding studies (i.e. Biacore, Octet)
  • Biophysical characterization of proteins, including thermofluor assays (DSF), isothermal titration calorimetry, DLS, and MALS
  • The design and execution of a variety of in vitro assays such as pull-downs, Western blots, and enzymatic reactions
  • Method development and validation
  • Supporting protein engineering/cloning, expression, and purification as needed

Basic Qualifications      

  • Bachelor's Degree in Protein Biochemistry or related field with 6+ years of research experience or Master's degree in Protein Biochemistry or related field with 3+ years of experience.
  • Hands-on experience with protein interaction studies paired with a variety of complementary biophysical techniques
  • Standard protein biochemistry techniques and protein handling/stability
  • Capable of performing literature searches and developing assays and experiments from scratch
  • Ability to work independently with minimal supervision
  • Effective oral and written communication skills, self-management, task planning and organization skills.
  • Demonstrated ability to work productively in a fast-paced team environment.

Preferred Qualifications

  • Hands-on experience with protein engineering, including familiarity with antibodies and fusion proteins
  • Protein expression and purification experience is preferred
  • Experience with enzymatic assays is preferred

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

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