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Senior Scientist, Neuromuscular Research, GMU

Framingham, Massachusetts



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Position Overview:

We are seeking a Senior Scientist to join the Genomics Medicine Unit and play a role in identifying strategies to treat neuromuscular disorders with a focus on muscular dystrophies and neuromuscular disease (e.g., Amyotrophic Lateral Sclerosis).  The successful candidate will support the development of viral and non-viral gene therapy strategies targeting and ensure successful translation of pre-clinical programs. 

Key Responsibilities:

Specifically, the remit of the candidate will be to:

  • Lead the technical development of novel gene therapy strategies for neuromuscular diseases.

  • Responsible for applying expertise to execute experiments and/or studies in a time sensitive manner.

  • Develop and maintain a culture of teamwork and collaboration.

  • Possess strong presentation and communication skills, and the ability to work in a team-oriented environment will be vital.

Basic Qualifications:

  • Ph.D. in  life science  with at least 2 - 3 years of post-doctoral experience or biotech/biopharma.

  • Demonstrated experience and expertise in muscle biology and/or ALS biology and pathogenesis; experience with animal models of neuromuscular disease is a plus.

  • In-depth knowledge in molecular biology with prior lab experience in perform DNA cloning, vector design, and construction, and plasmid preparations using standard and advanced molecular biology techniques.

  • Knowledgeable and skilled in designing and conducting in-vivo mouse studies and ex-vivo cell-based assays.

  • Experience in developing in vitro models to investigate the different gene therapy strategies.

  • Experience working with in vitro and in vivo disease models using molecular biology and histological techniques including DNA, RNA and protein extraction, immunohistochemistry, immunofluorescence, in-situ hybridization, western blot, qPCR, and ELISA.

  • Strong organizational skills and attention to detail.

  • Ability to effectively communicate ideas and document research.

  • Candidates must be authorized to work in the USA.

Sanofi US Services, Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.



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