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Scientist Downstream Process Development - VIE Contract (W/M)

Framingham, Massachusetts

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Overview

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    Comprehensive coverage including medical, dental, vision, and health and wellness programs.

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Quote

"At Sanofi, We are guided by a deep appreciation and understanding of what it means to live with a rare blood disorder, and we learn by listening to the community – patients, caregivers physicians, and other healthcare professionals."

Shannon Resetich US Head Rare Diseases & Blood Disorders

"Patients are at the center of all that we do at Sanofi. Our teams are focused on advancing transformational therapies that can address serious unmet needs for people living with rare blood disorders, and expanding global patient access to our medicines."

Mouhamed Gueye US Head Medical Rare Blood Disorders

Responsibilities

iMove, the Sanofi VIE Program, is available to citizens of the European Economic Area (EU + Norway, Liechtenstein and Iceland) aged between 18 and 28.

PLEASE NOTE that since this program is primarily an international development program, candidates cannot apply to a VIE assignment in their own country of citizenship.

PLEASE NOTE that applications that are only submitted in French cannot be considered by our non-French speaking partners at Sanofi worldwide.

Therefore, only applications that are submitted in English will be considered.

At Sanofi diversity and inclusion is foundational to how we operate and is embedded in our Core Values. We respect the diversity of our people, their backgrounds and experiences. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our employees, patients and customers.

We are looking for: Scientist Downstream Process Development  - VIE Contract (W/M)

Target start date: 01/05/2023

Responsibilities:

  • Work with a global group of engineers and scientists to develop robust and scalable downstream processes for monoclonal antibodies, bispecific antibodies, Fc-, Fab-, and fusion proteins, enzymes, and other recombinant proteins to support Good manufacturing practice (GMP)
  • Work on Manufacturing Science & Analytical Technology (MSAT) development and pilot-scale projects, including regular team meetings and updates for, data management, investigations, technical report writing, and regulatory filings
  • Support virus clearance studies to support regulatory filings including establishing scale-down models
  • Support technology transfer including projects for internal and external partners
  • Support Design of experiments (DOE) studies to establish proven and acceptable process ranges

Requirements:

  • M.S./M.A. in Biotechnology, or related field
  • A minimum of 1 year of full-time professional experience (at least 52 weeks) related to the role
  • Experience with downstream processes at the small to an intermediate scale of cGMP biologics production including chromatography and filtration
  • Prior experience in process scaling and or technology transfer
  • Prior experience with automated chromatography platforms (e.g., GE Healthcare AKTA)
  • Experience with authoring and executing protocols, interpretation of data, and generating final reports
  • Process-scale chromatography and filtration including Nano, tangential flow, and normal flow filtration
  • Experience writing and revising standard operating procedures and batch production records
  • Experience with operating and troubleshooting process equipment
  • Experience working on late phase and commercial programs
  • Fluent English
  • Proficiency with MS Office Package

At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

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