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Senior Research Associate, Dupixent Research, Immunology and Inflammation Therapeutic Area

Cambridge, Massachusetts

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"At Sanofi, We are guided by a deep appreciation and understanding of what it means to live with a rare blood disorder, and we learn by listening to the community – patients, caregivers physicians, and other healthcare professionals."

Shannon Resetich US Head Rare Diseases & Blood Disorders

"Patients are at the center of all that we do at Sanofi. Our teams are focused on advancing transformational therapies that can address serious unmet needs for people living with rare blood disorders, and expanding global patient access to our medicines."

Mouhamed Gueye US Head Medical Rare Blood Disorders


The Type 2 Inflammation and Dupixent Research cluster in the Immunology and Inflammation therapeutic area within Sanofi is seeking an experienced and highly motivated scientist to join their team. The candidate will help to expand our mechanistic understanding of Dupixent and maximize its value through execution of dedicated research studies. A successful candidate will have a background in immunology and an ability to integrate into multiple projects, contributing technical in vitro and in vivo skills. The candidate must be driven, resourceful, and able to work independently. Excellent organizational skills in management of data, reagents and equipment are essential. The candidate will participate in regular team meetings and present results, interpret data, and formulate conclusions. Teamwork, collaboration with colleagues across disciplines and excellent verbal and written communication skills are critical.   

Key Responsibilities

  • Design, execute and troubleshoot experiments using immunological and biochemical assays including flow cytometric and microscopic analysis, ELISAs, live-cell imaging, patch clamp electrophysiology and other functional assays. Hands-on laboratory contribution is essential.

  • Primary cell isolation, cell culture and maintenance.

  • Assist with in vivo pharmacology studies by performing intraperitoneal, intranasal, and intradermal administration of test substances and assisting with sample collection.

  • Coordinate studies with team members or inter/intra cluster colleagues and platforms.

  • Coordinate research efforts and makes key technical and intellectual contributions that affect the direction of the group and/or project.

  • Analyze, interpret, and document data and communicate results in team, group, and leadership settings and help decide next steps.

  • Maintain a compliant laboratory notebook.

  • Provide and promote support for operational excellence according to Sanofi values and ethics. 

  • Adhere to corporate standards of code of conduct, safety and disposal of controlled substances and biohazard material.

  • Work independently with minimal supervision

Basic Qualifications

  • Bachelor’s Degree plus a minimum of 4 years OR Master’s Degree plus a minimum of 1 year of relevant research experience in an academic or biopharmaceutical setting

  • Hands-on industry experience designing, executing, and documenting cell-based pharmacology experiments is preferred but not required.

Preferred Qualifications

  • Experience with experimental design, execution and troubleshooting.

  • Demonstrated background in cell biology:

    • Experience in aseptic technique for in vitro cell culture.

  • Experience with protein quantification platforms (e.g. ELISA, MSD, Luminex).

  • Experience with flow cytometry, patch clamp electrophysiology, live-cell imaging or fluorescence microscopy is desirable but not required.

  • Demonstrated ability to master new scientific disciplines, troubleshoot both technical and scientific problems, and analyze and interpret experimental data and suggest next steps.

  • Ability to effectively present and communicate complex data sets to diverse audiences.

  • Excellent organization, communication, presentation, and interpersonal skills.

  • Background/experience in immunology is a plus

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

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